Human Carbonic Anhydrase II (CA2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CA2
Locus ID	760
Kit Components	GA100528G1, Carbonic Anhydrase II gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100528G2, Carbonic Anhydrase II gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100528G3, Carbonic Anhydrase II gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000067, NM_001293675
Synonyms	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282
Summary	The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

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