Human CX3CR1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CX3CR1
Locus ID	1524
Kit Components	GA101079G1, CX3CR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101079G2, CX3CR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101079G3, CX3CR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001171171, NM_001171172, NM_001171174, NM_001337
Synonyms	CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28
Summary	Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

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