Human Cytochrome P450 2C8 (CYP2C8) activation kit by CRISPRa
CAT#: GA101099
CYP2C8 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 2 subfamily C member 8
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | CYP2C8 |
Locus ID | 1558 |
Kit Components | GA101099G1, Cytochrome P450 2C8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101099G2, Cytochrome P450 2C8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101099G3, Cytochrome P450 2C8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_000770, NM_001198853, NM_001198854, NM_001198855, NM_030878 |
Synonyms | CPC8; CYPIIC8; MP-12/MP-20 |
Summary | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN404605 | CYP2C8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |