Human GABA A Receptor delta (GABRD) activation kit by CRISPRa
CAT#: GA101706
GABRD CRISPRa kit - CRISPR gene activation of human gamma-aminobutyric acid type A receptor delta subunit
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | GABRD |
Locus ID | 2563 |
Kit Components | GA101706G1, GABA A Receptor delta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101706G2, GABA A Receptor delta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101706G3, GABA A Receptor delta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_000815 |
Synonyms | EIG10; EJM7; GEFSP5 |
Summary | Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN407591 | GABRD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |