Human GRB10 activation kit by CRISPRa
CAT#: GA101943
GRB10 CRISPRa kit - CRISPR gene activation of human growth factor receptor bound protein 10
CNY 12,255.00
CNY 1,999.00
CNY 2,700.00
CNY 3,992.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | GRB10 |
Locus ID | 2887 |
Kit Components | GA101943G1, GRB10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101943G2, GRB10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101943G3, GRB10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001001549, NM_001001550, NM_001001555, NM_005311, NM_001350814, NM_001350815, NM_001350816 |
Synonyms | Grb-10; GRB-IR; IRBP; MEG1; RSS |
Summary | The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN406853 | GRB10 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |