Human Glutathione Transferase zeta 1 (GSTZ1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GSTZ1
Locus ID	2954
Kit Components	GA102000G1, Glutathione Transferase zeta 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102000G2, Glutathione Transferase zeta 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102000G3, Glutathione Transferase zeta 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001312660, NM_001513, NM_145870, NM_145871, NM_001363703
Synonyms	GSTZ1-1; MAAI; MAI
Summary	This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme catalyzes the conversion of maleylacetoacetate to fumarylacetoacatate, which is one of the steps in the phenylalanine/tyrosine degradation pathway. Deficiency of a similar gene in mouse causes oxidative stress. Several transcript variants of this gene encode multiple protein isoforms. [provided by RefSeq, Jul 2015]

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