Human HLAE (HLA-E) activation kit by CRISPRa
CAT#: GA102138
HLA-E CRISPRa kit - CRISPR gene activation of human major histocompatibility complex, class I, E
CNY 12,255.00
货期*
4周
规格
经常一起买 (3)
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | HLA-E |
Locus ID | 3133 |
Kit Components | GA102138G1, HLAE gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102138G2, HLAE gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102138G3, HLAE gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_005516 |
Synonyms | HLA-6.2; QA1 |
Summary | HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Customer
Reviews
Loading...