Human CD49b (ITGA2) activation kit by CRISPRa

CAT#: GA102464

ITGA2 CRISPRa kit - CRISPR gene activation of human integrin subunit alpha 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
ITGA2 (Myc-DDK-tagged)-Human integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2)
    • 10 ug

CNY 12,336.00


Integrin alpha 2 (ITGA2/CD49b) Rabbit polyclonal Antibody
    • 100 ul

CNY 2,900.00

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol ITGA2
Locus ID 3673
Kit Components

GA102464G1, CD49b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102464G2, CD49b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102464G3, CD49b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_002203, NR_073103, NR_073104, NR_073105, NR_073106, NR_073107
Synonyms BR; CD49B; GPIa; HPA-5; VLA-2; VLAA2
Summary This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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