Human Integrin beta 1 (ITGB1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ITGB1
Locus ID	3688
Kit Components	GA102477G1, Integrin beta 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102477G2, Integrin beta 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102477G3, Integrin beta 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_002211, NM_033666, NM_033667, NM_033668, NM_033669, NM_133376
Synonyms	CD29; FNRB; GPIIA; MDF2; MSK12; VLA-BETA; VLAB
Summary	Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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