Human Menin (MEN1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MEN1
Locus ID	4221
Kit Components	GA102876G1, Menin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102876G2, Menin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102876G3, Menin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000244, NM_130799, NM_130800, NM_130801, NM_130802, NM_130803, NM_130804, NM_001370259, NM_001370261, NM_001370262, NM_001370251, NM_001370260, NM_001370263
Synonyms	MEAI; SCG2
Summary	This gene encodes menin, a tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. Menin is a scaffold protein that functions in histone modification and epigenetic gene regulation. It is thought to regulate several pathways and processes by altering chromatin structure through the modification of histones. [provided by RefSeq, May 2019]

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