Human Myeloid leukemia factor 1 (MLF1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MLF1
Locus ID	4291
Kit Components	GA102917G1, Myeloid leukemia factor 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102917G2, Myeloid leukemia factor 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102917G3, Myeloid leukemia factor 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001130156, NM_001130157, NM_001195432, NM_001195433, NM_001195434, NM_022443, NM_001369782, NM_001369784, NM_001369781, NM_001369783, NM_001369785
Synonyms	myeloid leukemia factor 1; myeloid leukemia factor 1 variant 1; myeloid leukemia factor 1 variant 2; myeloid leukemia factor 1 variant 3
Summary	This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

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