Human Myelin oligodendrocyte glycoprotein (MOG) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MOG
Locus ID	4340
Kit Components	GA102956G1, Myelin oligodendrocyte glycoprotein gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102956G2, Myelin oligodendrocyte glycoprotein gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102956G3, Myelin oligodendrocyte glycoprotein gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001008228, NM_001008229, NM_001170417, NM_001170418, NM_002433, NM_206809, NM_206810, NM_206811, NM_206812, NM_206813, NM_206814, NM_001363610
Synonyms	BTN6; BTNL11; MOGIG2; NRCLP7
Summary	The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

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