Human PARN activation kit by CRISPRa

CAT#: GA103387

PARN CRISPRa kit - CRISPR gene activation of human poly(A)-specific ribonuclease



  See Other Versions

CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
PARN mouse monoclonal antibody, clone OTI4D12 (formerly 4D12)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


PARN (Myc-DDK-tagged)-Human poly(A)-specific ribonuclease (deadenylation nuclease) (PARN), transcript variant 1
    • 10 ug

CNY 4,760.00


PARN mouse monoclonal antibody,clone OTI2D9
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PARN
Locus ID 5073
Kit Components

GA103387G1, PARN gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103387G2, PARN gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103387G3, PARN gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001134477, NM_001242992, NM_002582
Synonyms DAN; DKCB6; PFBMFT4
Summary The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...