Human PI 3 Kinase catalytic subunit gamma (PIK3CG) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PIK3CG
Locus ID	5294
Kit Components	GA103559G1, PI 3 Kinase catalytic subunit gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103559G2, PI 3 Kinase catalytic subunit gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103559G3, PI 3 Kinase catalytic subunit gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001282426, NM_001282427, NM_002649
Synonyms	p110gamma; p120-PI3K; PI3CG; PI3K; PI3Kgamma; PIK3
Summary	Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015]

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