Human Phosphoserine phosphatase (PSPH) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PSPH
Locus ID	5723
Kit Components	GA103889G1, Phosphoserine phosphatase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103889G2, Phosphoserine phosphatase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103889G3, Phosphoserine phosphatase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_004577, NM_001370503, NM_001370506, NM_001370507, NM_001370508, NM_001370510, NM_001370512, NM_001370515, NM_001370516, NM_001370518, NM_001370519, NM_001370520, NM_001370522, NM_001370504, NM_001370505, NM_001370509, NM_001370511, NM_001370513, NM_001370514, NM_001370517, NM_001370521
Synonyms	PSP; PSPHD
Summary	The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq, Jul 2008]

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