Human PYCR1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PYCR1
Locus ID	5831
Kit Components	GA103966G1, PYCR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103966G2, PYCR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103966G3, PYCR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001282279, NM_001282280, NM_001282281, NM_001330523, NM_006907, NM_153824
Synonyms	ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR
Summary	This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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