Human Nav1.8 (SCN10A) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SCN10A
Locus ID	6336
Kit Components	GA104301G1, Nav1.8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104301G2, Nav1.8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104301G3, Nav1.8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001293306, NM_001293307, NM_006514
Synonyms	FEPS2; hPN3; Nav1.8; PN3; SNS
Summary	The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits. This protein may be involved in the onset of pain associated with peripheral neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

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