Human SC35 (SRSF2) activation kit by CRISPRa

CAT#: GA104372

SRSF2 CRISPRa kit - CRISPR gene activation of human serine and arginine rich splicing factor 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
SRSF2 Rabbit polyclonal Antibody
    • 100 ul

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CNY 3,280.00

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SRSF2 (Myc-DDK-tagged)-Human serine/arginine-rich splicing factor 2 (SRSF2), transcript variant 1
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SC35 Rabbit monoclonal Antibody
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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol SRSF2
Locus ID 6427
Kit Components

GA104372G1, SC35 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104372G2, SC35 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104372G3, SC35 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001195427, NM_003016, NR_036608
Synonyms PR264; SC-35; SC35; SFRS2; SFRS2A; SRp30b
Summary The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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