Human SH3 containing Grb 2 like 1 protein (SH3GL1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SH3GL1
Locus ID	6455
Kit Components	GA104395G1, SH3 containing Grb 2 like 1 protein gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104395G2, SH3 containing Grb 2 like 1 protein gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104395G3, SH3 containing Grb 2 like 1 protein gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001199943, NM_001199944, NM_003025
Synonyms	CNSA1; EEN; SH3D2B; SH3P8
Summary	This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

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