Human TCF12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TCF12
Locus ID	6938
Kit Components	GA104787G1, TCF12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104787G2, TCF12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104787G3, TCF12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001306219, NM_001306220, NM_003205, NM_207036, NM_207037, NM_207038, NM_207040, NM_001322151, NM_001322152, NM_001322154, NM_001322156, NM_001322157, NM_001322158, NM_001322159, NM_001322161, NM_001322162, NM_001322164, NM_001322165
Synonyms	bHLHb20; CRS3; HEB; HsT17266; HTF4
Summary	The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

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