Human PEA15 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PEA15
Locus ID	8682
Kit Components	GA105759G1, PEA15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105759G2, PEA15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105759G3, PEA15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001297576, NM_001297577, NM_001297578, NM_003768, NM_013287, NR_123724
Synonyms	HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PED
Summary	This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

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