Human ALKBH1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ALKBH1
Locus ID	8846
Kit Components	GA105887G1, ALKBH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105887G2, ALKBH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105887G3, ALKBH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001039506, NM_006020
Synonyms	ABH; ABH, alkB, hABH, ALKBH; ABH1; alkB; alkB, alkylation repair homolog 1 (E. coli); ALKBH; alkylated DNA repair protein alkB homolog; alkylation repair, alkB homolog; hABH
Summary	This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. [provided by RefSeq, Jul 2008]

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