Human Transglutaminase 5 (TGM5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TGM5
Locus ID	9333
Kit Components	GA106222G1, Transglutaminase 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106222G2, Transglutaminase 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106222G3, Transglutaminase 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_004245, NM_201631
Synonyms	PSS2; TGASE5; TGASEX; TGM6; TGMX; TGX
Summary	This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome. [provided by RefSeq, Oct 2009]

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