Human PERK (EIF2AK3) activation kit by CRISPRa

CAT#: GA106311

EIF2AK3 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 2 alpha kinase 3



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Anti-EIF2AK3 Rabbit Polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


EIF2AK3 (Myc-DDK-tagged)-Human eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3)
    • 10 ug

CNY 11,656.00


PERK Rabbit monoclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol EIF2AK3
Locus ID 9451
Kit Components

GA106311G1, PERK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106311G2, PERK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106311G3, PERK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001313915, NM_004836
Synonyms PEK; PERK; WRS
Summary The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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