Human UBE3C activation kit by CRISPRa
CAT#: GA106502
UBE3C CRISPRa kit - CRISPR gene activation of human ubiquitin protein ligase E3C
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | UBE3C |
Locus ID | 9690 |
Kit Components | GA106502G1, UBE3C gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106502G2, UBE3C gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106502G3, UBE3C gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_014671 |
Synonyms | HECTH2 |
Summary | E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN415110 | UBE3C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |