Human ST18 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ST18
Locus ID	9705
Kit Components	GA106516G1, ST18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106516G2, ST18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106516G3, ST18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_014682, NM_001352826, NM_001352827, NM_001352828, NM_001352829, NM_001352830, NM_001352831, NM_001352832, NM_001352833, NM_001352834, NM_001352835, NM_001352836, NM_001352837, NM_001352838, NM_001352839, NM_001352840, NM_001352841, NM_001352842, NM_001352843, NM_001352844, NM_001352845, NM_001352846, NM_001352847, NM_001352848, NM_001352849, NM_001352850, NM_001352851, NM_001352852, NM_001352853, NM_001352854, NM_001352855, NM_001352856, NM_001352857, NM_001352858, NM_001352859, NM_001352860, NM_001352861, NM_001352862, NM_001352863, NM_001352864, NM_001352865, NM_001352866, NM_001352867, NM_001352868, NM_001352869, NM_001352870, NM_001352871, NM_001352872, NM_001352873, NM_001352874, NM_001352875, NM_001352876, NM_001352877, NM_001352878, NM_001352879, NM_001352880, NM_001352881, NM_001352882, NM_001352883, NM_001352884, NR_148195, NR_148196
Synonyms	NZF3; ZC2HC10; ZNF387
Summary	Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). Inhibits colony formation in cultured breast cancer cells.[UniProtKB/Swiss-Prot Function]

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