Human NSP3 (SH2D3C) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SH2D3C
Locus ID	10044
Kit Components	GA106801G1, NSP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106801G2, NSP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106801G3, NSP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001142531, NM_001142532, NM_001142533, NM_001142534, NM_001252334, NM_005489, NM_170600
Synonyms	CHAT; NSP3; PRO34088; SHEP1
Summary	This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

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