Human KLRG1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KLRG1
Locus ID	10219
Kit Components	GA106949G1, KLRG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106949G2, KLRG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106949G3, KLRG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001329099, NM_001329101, NM_001329102, NM_001329103, NM_005810, NR_137426, NR_137427, NR_137428
Synonyms	2F1; CLEC15A; MAFA; MAFA-2F1; MAFA-L; MAFA-LIKE
Summary	Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016]

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