Human Influenza Virus NS1A Binding Protein (IVNS1ABP) activation kit by CRISPRa

CAT#: GA107276

IVNS1ABP CRISPRa kit - CRISPR gene activation of human influenza virus NS1A binding protein



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Cited in 1 publication.

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-IVNS1ABP Antibody
    • 100 ul

CNY 5,250.00


IVNS1ABP (Myc-DDK-tagged)-Human influenza virus NS1A binding protein (IVNS1ABP)
    • 10 ug

CNY 4,784.00


IVNS1ABP Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol IVNS1ABP
Locus ID 10625
Kit Components

GA107276G1, Influenza Virus NS1A Binding Protein gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA107276G2, Influenza Virus NS1A Binding Protein gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA107276G3, Influenza Virus NS1A Binding Protein gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_006469, NM_016389
Synonyms FLARA3; HSPC068; KLHL39; ND1; NS-1; NS1-BP; NS1BP
Summary Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (By similarity). Protects cells from cell death induced by actin destabilization (By similarity). Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription (PubMed:16582008). In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors (PubMed:25619834). Inhibits pre-mRNA splicing (in vitro) (PubMed:9696811).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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