Human iASPP (PPP1R13L) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPP1R13L
Locus ID	10848
Kit Components	GA107429G1, iASPP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107429G2, iASPP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107429G3, iASPP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001142502, NM_006663
Synonyms	IASPP; NKIP1; RAI; RAI4
Summary	IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008]

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