Human USP19 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	USP19
Locus ID	10869
Kit Components	GA107443G1, USP19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107443G2, USP19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107443G3, USP19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001199160, NM_001199161, NM_001199162, NM_006677, NM_001351098, NM_001351099, NM_001351100, NM_001351101, NM_001351102, NM_001351103, NM_001351104, NM_001351105, NM_001351106, NM_001351107, NM_001351108
Synonyms	ZMYND9
Summary	Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This protein is a ubiquitin protein ligase and plays a role in muscle wasting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]

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