Human SEMCAP3 (PDZRN3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PDZRN3
Locus ID	23024
Kit Components	GA107977G1, SEMCAP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107977G2, SEMCAP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107977G3, SEMCAP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001303139, NM_001303140, NM_001303141, NM_001303142, NM_015009
Synonyms	LNX3; SEMACAP3; SEMCAP3
Summary	This gene encodes a member of the LNX (Ligand of Numb Protein-X) family of RING-type ubiquitin E3 ligases. This protein may function in vascular morphogenesis and the differentiation of adipocytes, osteoblasts and myoblasts. This protein may be targeted for degradation by the human papilloma virus E6 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

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