Human IL17RA activation kit by CRISPRa

CAT#: GA108494

IL17RA CRISPRa kit - CRISPR gene activation of human interleukin 17 receptor A



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-IL17RA Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


IL17RA (Myc-DDK-tagged)-Human interleukin 17 receptor A (IL17RA)
    • 10 ug

CNY 9,512.00


Rabbit Polyclonal IL17RA Antibody
    • 100 ug

CNY 5,302.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol IL17RA
Locus ID 23765
Kit Components

GA108494G1, IL17RA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108494G2, IL17RA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108494G3, IL17RA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001289905, NM_014339
Synonyms CANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R
Summary Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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