Human Kallikrein 13 (KLK13) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KLK13
Locus ID	26085
Kit Components	GA108741G1, Kallikrein 13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108741G2, Kallikrein 13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108741G3, Kallikrein 13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_015596, NM_001348177, NM_001348178, NR_145463, NR_145464, NR_145465, NR_145466, NR_145467
Synonyms	KLK-L4; KLKL4
Summary	Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. [provided by RefSeq, Jan 2017]

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