Human GTP binding protein era homolog (ERAL1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ERAL1
Locus ID	26284
Kit Components	GA108844G1, GTP binding protein era homolog gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108844G2, GTP binding protein era homolog gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108844G3, GTP binding protein era homolog gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001317985, NM_001317986, NM_005702, NR_134328
Synonyms	CEGA; ERA; ERA-W; ERAL1A; H-ERA; HERA-A; HERA-B
Summary	The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

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