Human Kallikrein 12 (KLK12) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KLK12
Locus ID	43849
Kit Components	GA109407G1, Kallikrein 12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109407G2, Kallikrein 12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109407G3, Kallikrein 12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_019598, NM_145894, NM_145895, NM_001370125, NM_001370126, NM_001370127, NM_001370128
Synonyms	KLK-L5; KLKL5
Summary	Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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