Human Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DYNC1LI1
Locus ID	51143
Kit Components	GA109602G1, Cytoplasmic dynein 1 light intermediate chain 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109602G2, Cytoplasmic dynein 1 light intermediate chain 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109602G3, Cytoplasmic dynein 1 light intermediate chain 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001329135, NM_016141
Synonyms	DLC-A; DNCLI1; LIC1
Summary	The protein encoded by this gene belongs to light intermediate subunit family, whose members are components of the multiprotein cytoplasmic dynein complex, which is involved in intracellular trafficking and chromosome segregation during mitosis. The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles. The protein may also mediate binding to other cargo molecules to facilitate intracellular vesicle trafficking. [provided by RefSeq, Jul 2016]

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