Human Glycoprotein VI (GP6) activation kit by CRISPRa
CAT#: GA109650
GP6 CRISPRa kit - CRISPR gene activation of human glycoprotein VI platelet
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | GP6 |
Locus ID | 51206 |
Kit Components | GA109650G1, Glycoprotein VI gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109650G2, Glycoprotein VI gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109650G3, Glycoprotein VI gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001083899, NM_001256017, NM_016363 |
Synonyms | BDPLT11; GPIV; GPVI |
Summary | This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN414355 | GP6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |