Human STYXL1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	STYXL1
Locus ID	51657
Kit Components	GA109927G1, STYXL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109927G2, STYXL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109927G3, STYXL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001317785, NM_001317786, NM_001317787, NM_001317788, NM_001317789, NM_016086, NR_134486, NR_134487
Synonyms	DUSP24; MK-STYX; MKSTYX
Summary	Catalytically inactive phosphatase (PubMed:20180778, PubMed:23163895). By binding to G3BP1, inhibits the formation of G3BP1-induced stress granules (PubMed:20180778, PubMed:23163895). Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149' (PubMed:23163895). Inhibits PTPMT1 phosphatase activity (PubMed:24709986). By inhibiting PTPMT1, positively regulates intrinsic apoptosis (PubMed:21262771). May play a role in the formation of neurites during neuronal development (PubMed:29250526).[UniProtKB/Swiss-Prot Function]

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