Human TM6SF2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TM6SF2
Locus ID	53345
Kit Components	GA110005G1, TM6SF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110005G2, TM6SF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110005G3, TM6SF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001001524, NM_203510
Synonyms	KIAA1926
Summary	Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content (PubMed:24531328, PubMed:24927523). May function as sterol isomerase (PubMed:25566323).[UniProtKB/Swiss-Prot Function]

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