Human CDK5RAP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CDK5RAP2
Locus ID	55755
Kit Components	GA110941G1, CDK5RAP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110941G2, CDK5RAP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110941G3, CDK5RAP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001011649, NM_001272039, NM_018249, NR_073554, NR_073555, NR_073556, NR_073557, NR_073558
Synonyms	C48; Cep215; MCPH3
Summary	This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

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