Human CSGALNACT1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CSGALNACT1
Locus ID	55790
Kit Components	GA110972G1, CSGALNACT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110972G2, CSGALNACT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110972G3, CSGALNACT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001130518, NM_018371, NR_024040, NM_001354475, NM_001354476, NM_001354477, NM_001354480, NM_001354481, NM_001354483, NM_001354484, NM_001354485, NM_001354487, NM_001354488, NM_001354489, NM_001354490, NM_001354491, NM_001354492, NM_001354494, NM_001354495, NM_001354496, NM_001354497, NM_001354498, NM_001354499, NR_148897, NR_148898, NR_148899, NR_148900, NR_148901, NR_148902
Synonyms	beta4GalNAcT; ChGn; CSGalNAcT-1
Summary	This gene encodes an enzyme that transfers N-acetylglucosamine (GalNAc) to the core tetrasaccharide linker and to elongating chondroitin sulfate chains in proteoglycans. Knockout of the orthologous mouse gene indicates that the protein is necessary for normal cartilage development and aggrecan metabolism. Mutations in this gene are associated with multiple sclerosis progression, and with mild skeletal dysplasia and joint laxity. [provided by RefSeq, Aug 2017]

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