Human RARS2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RARS2
Locus ID	57038
Kit Components	GA111345G1, RARS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111345G2, RARS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111345G3, RARS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001318785, NM_020320, NR_134857, NM_001350505, NM_001350506, NM_001350507, NM_001350508, NM_001350509, NM_001350510, NM_001350511, NR_146738, NR_146739, NR_146740, NR_146741, NR_146742, NR_146743, NR_146744, NR_146745, NR_146746, NR_146747, NR_146748, NR_146749, NR_146750, NR_146751, NR_146752, NR_146753, NR_146754, NR_146755, NR_146756, NR_146757, NR_146758, NR_146759
Synonyms	ArgRS; DALRD2; dJ382I10.6; PCH6; PRO1992; RARSL
Summary	This nuclear gene encodes a protein that localizes to the mitochondria, where it catalyzes the transfer of L-arginine to its cognate tRNA, an important step in translation of mitochondrially-encoded proteins. Defects in this gene are a cause of pontocerebellar hypoplasia type 6 (PCH6). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

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