Human MTUS1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MTUS1
Locus ID	57509
Kit Components	GA111547G1, MTUS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111547G2, MTUS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111547G3, MTUS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001001924, NM_001001925, NM_001001927, NM_001001931, NM_001166393, NM_001330470, NM_020749, NM_001363057, NM_001363059, NM_001363061, NM_001363062, NM_001363058, NM_001363060, NR_156437
Synonyms	ATBP; ATIP; ICIS; MP44; MTSG1
Summary	This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]

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