Human PAPP A2 (PAPPA2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PAPPA2
Locus ID	60676
Kit Components	GA111880G1, PAPP A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111880G2, PAPP A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111880G3, PAPP A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_020318, NM_021936
Synonyms	PAPP-A2; PAPP-E; PAPPE; PLAC3
Summary	This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]

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