Human Melanophilin (MLPH) activation kit by CRISPRa
CAT#: GA112355
MLPH CRISPRa kit - CRISPR gene activation of human melanophilin
CNY 12,255.00
CNY 1,999.00
CNY 2,700.00
CNY 4,464.00
CNY 4,560.00
CNY 800.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | MLPH |
Locus ID | 79083 |
Kit Components | GA112355G1, Melanophilin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112355G2, Melanophilin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112355G3, Melanophilin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001042467, NM_001281473, NM_001281474, NM_024101, NR_104019 |
Synonyms | SLAC2-A |
Summary | This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN400895 | MLPH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |