Human DYNC2H1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DYNC2H1
Locus ID	79659
Kit Components	GA112526G1, DYNC2H1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112526G2, DYNC2H1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112526G3, DYNC2H1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001080463, NM_001377, NM_024606
Synonyms	ATD3; DHC1b; DHC2; DNCH2; DYH1B; hdhc11; SRPS2B; SRTD3
Summary	This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010]

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