Human FBXL18 activation kit by CRISPRa
CAT#: GA112800
FBXL18 CRISPRa kit - CRISPR gene activation of human F-box and leucine rich repeat protein 18
CNY 12,255.00
CNY 5,256.00
CNY 5,800.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | FBXL18 |
Locus ID | 80028 |
Kit Components | GA112800G1, FBXL18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112800G2, FBXL18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112800G3, FBXL18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_024963, NM_001321213, NM_001363441, NM_001363442, NM_001367780, NM_001367781 |
Synonyms | Fbl18 |
Summary | The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7, a protein that induces mitotic arrest, by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. [provided by RefSeq, Mar 2016] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN420401 | FBXL18 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |