Human Rho GTPase activating protein 24 (ARHGAP24) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGAP24
Locus ID	83478
Kit Components	GA113184G1, Rho GTPase activating protein 24 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113184G2, Rho GTPase activating protein 24 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113184G3, Rho GTPase activating protein 24 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001025616, NM_001042669, NM_001287805, NM_031305, NM_001346093
Synonyms	FILGAP; p73; p73RhoGAP; RC-GAP72; RCGAP72
Summary	This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.