Human Transmembrane Protein 175 (TMEM175) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TMEM175
Locus ID	84286
Kit Components	GA113483G1, Transmembrane Protein 175 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113483G2, Transmembrane Protein 175 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113483G3, Transmembrane Protein 175 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001297423, NM_001297424, NM_001297425, NM_001297426, NM_001297427, NM_001297428, NM_032326
Synonyms	hTMEM175
Summary	Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel.[UniProtKB/Swiss-Prot Function]

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